Drug Studies in the Elderly: Methodological Concerns

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For a treatment to become standard, it must first go through 3 or 4 clinical trial phases. The early phases make sure the treatment is safe. Later phases show if it works better than the standard treatment. Each phase of a clinical trial is designed to provide different information about the new treatment, such as the dose, safety, and efficacy how well it works.

Data are collected on the dose, timing, and safety of the treatment. The purpose is to evaluate its safety and identify side effects. Phase II trials usually take about two years to complete. At least two and often more than two treatment options, including standard of care are compared to find out whether the new treatment is better, and possibly has fewer side effects, than the current standard treatment.

Phase III clinical trials are usually randomized, meaning that patients receive either the investigational drug or treatment or another drug or treatment in a non-ordered way. Several hundred to several thousand people participate in Phase IV trials. Its research domains are individuals, families, organizations, institutions, communities, and populations. View access options below. You previously purchased this article through ReadCube.

Methodological Issues in Conducting Treatment Trials for Psychological Nonepileptic Seizures

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Search within Contents Front Matter Preface to the fifth edition Introduction to Volume 1: The scope of public health Introduction to Volume 2: The methods of public health Introduction to Volume 3: The practice of public health List of contributors Volume 1 The scope of public health Section 1 The development of the discipline of public health 1. Disclaimer Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct.

Show Summary Details Preface to the fifth edition Introduction to Volume 1: The scope of public health Introduction to Volume 2: The methods of public health Introduction to Volume 3: The practice of public health List of contributors Section 1 The development of the discipline of public health Section 2 Determinants of health and disease Section 3 Public health policies Section 4 Public health law and ethics Section 5 Information systems and sources of intelligence Section 6 Epidemiological and biostatistical approaches 6.

Preface to the fifth edition Introduction to Volume 1: The scope of public health Introduction to Volume 2: The methods of public health Introduction to Volume 3: The practice of public health List of contributors Section 1 The development of the discipline of public health Section 2 Determinants of health and disease Section 3 Public health policies Section 4 Public health law and ethics Section 5 Information systems and sources of intelligence Section 6 Epidemiological and biostatistical approaches 6. All rights reserved. Sign in to annotate. Delete Cancel Save.

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